Bryan Johnson Reveals Diagnosis of Rare Incurable Autoimmune Disease After Years of Unexplained Health Issues

Tech entrepreneur and longevity advocate Bryan Johnson has revealed that he has been diagnosed with autoimmune gastritis (AIG), a rare chronic condition in which the body’s immune system mistakenly attacks the stomach lining.

The 48-year-old billionaire, widely known for his ambitious anti-aging experiments and the Blueprint longevity project, shared that the diagnosis came after years of unexplained low iron levels that puzzled both him and his medical team.

According to Johnson, doctors carried out a series of medical evaluations, including blood tests, an endoscopy and stomach biopsies, which ultimately confirmed he was living with autoimmune gastritis.

The condition gradually damages the stomach lining, making it difficult for the body to absorb essential nutrients such as iron and vitamin B12. As a result, patients face an increased risk of iron-deficiency anaemia, vitamin B12 deficiency and, in some cases, stomach cancer.

Although autoimmune gastritis currently has no cure, Johnson said he has already begun treatment to manage the condition. His care plan includes regular iron infusions to address his chronic deficiency, alongside ongoing medical monitoring to detect and manage any potential complications at an early stage.

Johnson has become one of the world’s most recognised figures in the longevity and biohacking movement, attracting global attention for spending millions of dollars annually on treatments, strict nutrition plans and advanced medical testing aimed at slowing the aging process. He also made headlines after participating in an experimental blood plasma exchange involving his son as part of his broader anti-aging research.

Despite his extensive health optimisation efforts, Johnson’s latest diagnosis highlights that even individuals with access to cutting-edge healthcare and preventive medicine can develop complex autoimmune conditions.

By publicly sharing his diagnosis, Johnson hopes to raise awareness about autoimmune gastritis, a disease that often goes undetected for years because its symptoms can be subtle or mistaken for other digestive disorders. His experience also underscores the importance of early medical evaluation for persistent nutrient deficiencies, particularly unexplained low iron levels.